Welcome Di Hu to the lab!

Di Hu has joined the neurogenomics lab this week! She did her PhD at the University of Oxford as a Clarendon Scholar in the laboratory of Professor Shankar Srinivas. There she investigated how transcription factor ETS2 may act as either an oncogene or tumour suppressor, using a combination of single-cell RNA-sequencing, FACS, high resolution fixed and live imaging, ex vivo pharmacological culture, and in vivo CRISPR genetics.

She then went on to pursue epigenetic research as a Postdoctoral Scientist in the laboratory of Professor Petra Hajkova at London Institute of Medical Sciences MRC. Her project involved uncovering molecular triggers for mouse germ cell epigenetic reprogramming using low-input RNA sequencing, FACS, mass spectrometry, embryonic stem cell derivation and directed differentiation, mathematical modelling, and bioinformatic approaches.

She’s now joined our lab to work towards her long-term goal of studying disease mechanisms of neurodegeneration. She’ll be investigating cell type specific epigenetic and molecular underpinnings of neurodegenerative disease as a joint Research Associate working with both Dr Nathan Skene and Dr Sarah Marzi.

Outside of science, she’s also a resident DJ who goes by the name ‘clarity’! We’re really excited to have her with us.

Nathan Skene
Nathan Skene
Lecturer and UKDRI Group Leader

My research interests include human genetics, single cell -omics and neurobiology.