I conducted my doctoral training at the University of Oxford as a Clarendon Scholar in the laboratory of Professor Shankar Srinivas. There I investigated how transcription factor ETS2 may act as either an oncogene or tumour suppressor, using a combination of single-cell RNA-sequencing, FACS, high resolution fixed and live imaging, ex vivo pharmacological culture, and in vivo CRISPR genetics.
I went on to pursue epigenetic research as a Postdoctoral Scientist in the laboratory of Professor Petra Hajkova at London Institute of Medical Sciences MRC. My project involved uncovering molecular triggers for mouse germ cell epigenetic reprogramming using low-input RNA sequencing, FACS, mass spectrometry, embryonic stem cell derivation and directed differentiation, mathematical modelling, and bioinformatic approaches.
With a long-term goal of studying disease mechanisms of neurodegeneration, I am now investigating cell type specific epigenetic and molecular underpinnings of neurodegenerative disease as a joint Research Associate in the laboratories of Dr Nathan Skene and Dr Sarah Marzi.
DPhil in Physiology, Anatomy and Genetics, 2019
University of Oxford
Anatomy and Cell Biology, 2014